instruments. Anyone with a specific question about any area of apheresis should be able to find the answer with this book, either in the references cited or, in most cases, in the text itself. An eclectic group of contributors have come together to produce Apheresis: Principles and Practices, 2nd edition including engineers and inventors involved in the development of instruments, physicians with expertise in apheresis and the treatment of diseases for which apheresis products or procedures are important therapeutically, nurses and technologists who care for donors and patients during apheresis procedures, and individuals with knowledge of regulatory and managerial issues. This book is intended for health-care professionals working in any branch of apheresis donation or therapy and should be useful for individuals at all levels in the blood banking and transfusion medicine communities, as well as physicians and other medical professionals who care for patients needing apheresis products or procedures. Highlights: Significant updates concerning adverse reactions, particularly those related to citrate and hypocalcemiaDescriptions of new instruments intended for multiple component donationsNew material on leukocyte reduction of apheresis plateletsNew chapter on bacterial contamination of platelet transfusionsNew information regarding the rapidly moving field of agents used to mobilize progenitor cells into the peripheral blood, the procedures that have been developed to collect them and the important issues of potency and tumor cell contaminationNew information on dendritic cellsUpdates to chapter on strategies using allogeneic donor cells with information provided by both basic and clinical studiesRevisions to information on photopheresis including results of recent clinical studies and a description of a new instrumentResults from the latest gene therapy trialsUpdates to the latest concepts and regulatory requirements

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