of new data from treatment trials and guideline comittees. The management guidelines of the Seventh Joint National Committee (JNC) on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure are again reviewed and critiqued in view of new data since these were originally published in 2003. The validity of advising a thiazide diuretic as initial therapy is put in perspective. The 2007 European Society of Hypertension and Society of Cardiology guidelines and new treatment algorithms are also reviewed and evaluated. Recently introduced antihypertensive agents, such as a renin inhibitor and a beta blocker with nitric oxide-enhancing properties, as well as newer combination therapies, are discussed. Above all, this updated edition of Clinical Management of Hypertension sends a clear message that more individuals with hypertension, especially in the older age groups, shoud be treated; effective and safe treatment is available; and achieving levels of BP as close to normal as possible-120-130/80 mm Hg-will reduce morbidity and mortality to an even greater degree than has occured to date.

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