methods and a complete presentation of results. It includesrefined methods to assess data, ensure epidemiological consistency, andsummarize the disease burden. 'Global Burden of Disease and Risk Factors' examines the comparative importance of diseases, injuries, and risk factors; it incorporates a range of new data sources to develop consistent estimates of incidence, prevalence, severity and duration, and mortality for 136 major diseases and injuries.Drawing from more than 8,500 data sources that include epidemiological studies, disease registers, and notifications systems, 'Global Burden of Disease and Risk Factors' incorporates informationfrom more than 10,000 datasets relating to population health and mortality, representing one of the largest syntheses of global information on population health to date.

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