bioelectricity. The clear presentation of key concepts and the excellent diagrams accompanying the text make this book a uniquely accessible introduction to a complex area of physiology. The Second Edition's coverage of membranes and synaptic transmission has been greatly expanded to reflect the many new developments in these areas. Highlights of the Second Edition include a new chapter on ion diffusion through biological membranes; more advanced material on ion permeation; a more extensive discussion of osmosis; and significantly expanded coverage of synaptic transmission in the central nervous system and synaptic plasticity. The expanded Appendix includes a description of some of the specialized membrane conductances and mechanisms that have specific roles in determining the firing pattern and integrative action of individual neurons.

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