Francis Collins is leading the Human Genome Project at the National Institutes of Health. Norma Riccucci presents a case study of how Dr. Helene Gayle led the nation's fight against HIV/AIDS and other sexually transmitted diseases. Beryl Radin analyzes the leadership style of Donna Shalala at the Department of Health and Human Services. Robert B. Denhardt and Janet Vinzant Denhardt present case studies of three local government leaders who are redefining the job of the local government executives. Paul A. Teske and Mark Schneider describe how principals are changing the New York City school system. Mark Huddleston presents his conversations with the federal government's leading senior civil servants. From these case studies, Mark A. Abramson and Kevin M. Bacon describe how 21st century leaders differ from their predecessors and what organizations can do today to develop future 21st century leaders.

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