a diagnosis in the skeleton by applying what are referred to as "operational definitions." The aim is to ensure that all those who study bones will use the same criteria for diagnosing disease, which will enable valid comparisons to be made between studies. This book is based on modern clinical knowledge and provides background information so that those who read will understand the natural history of bone diseases, and this will enable them to draw reliable conclusions from their observations. Details of bone metabolism and the fundamentals of basic pathology are also provided, as well as a comprehensive and up-to-date bibliography. A short chapter on epidemiology provides information on how best to analyze and present the results of a study of human remains.

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