prostate cancers is 70%, whereas it is only 30 to 40%in metastatic lung cancer. In clinical terms, bone metastases havesubstantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attentionbecause of the difficulty in quantifying them, which has left themoutside the scope of therapeutic trialsThis textbook is the result of the remarkable progress made inthe understanding of the molecular and cellular mechanisms involvedin osteogenesis and osteolysis, and their development fortherapeutic purposes. The treatment of malignant hypercalcaemia hasalso been revolutionised by the use of bisphosphonates.The Textbook of Bone Metastases presents a broad approachto recent progress in all fields related to bone metastases,ranging from epidemiology to the physiopathology of bone metastasesand therapeutics. It provides a better understanding of recentadvances and, more importantly, will give clinicians all theinformation needed to help them in the clinical and therapeuticmanagement of patients with bone metastases.

Hide more