manipulated without affecting other sites. The book emphasizes the link between the mechanisms of organic chemistry and the choice of specific protecting groups that block chemical reactivity at those sites that must remain unaffected. The treatment differs from traditional texts in that it places the emphasis on making a connection between the fundamental mechanisms of organic chemisry - ionization, substitution, addition, elimination, oxidation, and reductionand how a particular protecting group can best be selected in a given situation.

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