Created by Dr. Phil Stephens of Villanova University, this online or CD program offers 37 self-contained laboratory simulations that may be used either to supplement or replace wet labs. Ph.I.L.S. allows students to perform experiments according to their own schedules, without risk of harm to themselves or live animals, and also without having to use expensive lab equipment (like Biopac, IWORX or Intellitool). Students can adjust variables, view outcomes, make predictions, draw conclusions, quiz themselves, and print lab reports. There is no limit to the number of times students can repeat each exercise, and the results differ every time the student changes the variables.

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