continues the role established by its predecessor as the leading work in the field. Mechanical ventilation, as a defining event of critical care, has seen an explosion of physiologic and outcomes research in the past decade. Our thinking about management of ARDS, ventilator-induced lung injury, patient-ventilator interaction, and infectious complications has changed dramatically. All of this recent work is summarized here."--Doody's Review Service Editor Martin J. Tobin--past editor-in-chief of the American Journal of Respiratory and Critical Care Medicine--has completely revised this text, acclaimed by The Lancet as "the bible of mechanical ventilation." The new edition is a cover-to-cover revision of the original content, filled with cutting-edge scientific insights from more than 200 contributors representing critical care, pulmonary medicine, anesthesiology, surgery, basic science, and radiology. Features: Up-to-the minute, rigorous coverage that addresses every important scientific, clinical, and technical aspect of the field 70 well-organized chapters that encompass the full scope of mechanical ventilation, including the physical basis of mechanical ventilation; conventional, alternative, noninvasive, and unconventional methods of ventilator support; complications and airway management; and ethics and economics 24 new chapters on current issues in mechanical ventilation: Closed Loop Ventilation, Inhaled Antibiotic Therapy, Sleep and Speech in the Ventilated Patient, Mechanical Ventilation in ARDS, Ventilation Outside the ICU, and more Highly relevant new chapters on pharmacological and adjuvant therapy Greater use of tables and lists that conveniently summarize key information and solidify chapter concepts

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